摘要近年来.随着脓毒症和多器官功能障碍综合征(multiple organ dysfunction syndrome,MODS)研究的不断发展,胃肠道功能的重要性越来越为广大从事重症医学领域的医护人员所认识。胃肠道作为人体内最大的“储菌库”和“内毒素库”,如果肠黏膜屏障完整性和保护功能遭到各种原因的破坏,
1American College of Chest Physicians / Society of CriticalCare Medicine Consensus Conference. Definitions for sepsisand multiple organ failure and guidelines for the use of in-novative therapies in sepsis[J]. Crit Care Med, 1992,20(6):864-874.
2Marshall JC, Cook DJ, Christou NV, et al. Multiple organdysfunction score : A reliable descriptor of a complex clinicaloutcome[J]. Crit Care Med ,1995,23 (10) : 1638-1652.
7Tytgat G N J. The role of cisapride in maintanance therapy for gastroesophageal disease (GERD) [J]. Motility, 1996,8:3-4.
8MacLaren R, Kuhl D A, Gervasio M, et al. Sequential single doses of cisapride, erythromycin, and metoclopramide in critically ill patients in tolerant to enterae nutrition : a randomized,placebo -controlled, crossover study [J]. Crit Care Med,2000,28:438 - 444.
9Wood S F. Cisapride in functional dyspepsia,a double blind placebo -controlled randomized trail in general practice patient [J]. Scan J Gastroenterol, 1993,195(Suppl) :5 - 14.
10Vander H R R W J, Soeters P B. Glutamine and the preservation of gut integrity[J]. Lancet, 1993,341 : 1363.