摘要
Sclerosing epithelioid fibrosarcoma(SEF)is a rare and poorly defined variant of fibrosarcoma,but generally insensitive to chemotherapy and progresses with poor prognosis.We report the marvelous effect of irinotecan hydrochloride(CPT-11)chemotherapy in rescuing a patient with atypical SEF from emergent condition,who underwent recurrences after several treatment methods.Small dose of CPT-11 was administered to the patient,with which,the size of superficial mass(cervical lymph node)gradually decreased observed by the naked eyes in 5 days.X-ray and CT image proved a marked reduction in the size of the tumor.CPT-11 is valuable for the treatment of this aggressive sarcoma.In condition of emergency caused by sarcoma oppression,administering a tolerable small dose of topoisomerase I-inhibiting drug could be a beneficial choice.
基金
supported by a grant from Science and Technology Committee of Guangdong(No.2010B060900093)
a grant from Educational Commission of Guangzhou(No.10A196)
