摘要
目的:观察脉血康胶囊对脑梗死恢复期患者临床疗效及其对凝血功能影响。方法:将120例恢复期脑梗死患者随机分为治疗组和对照组。对照组50例采用常规治疗,治疗组70例在常规治疗基础上加用脉血康胶囊治疗3个月,治疗前后分别测定神经功能缺损评分及凝血酶原时间(PT)、活化部分凝血酶时间(APTT)、凝血酶时间(TT)、纤维蛋白原(Fib)水平。结果:治疗后治疗组PT,APTT,TT较治疗前时间延长(P<0.05),Fib、神经功能缺损评分下降(P<0.01),且与对照组治疗后比较差异明显(P<0.05)。结论:脉血康胶囊是治疗脑梗死恢复期患者安全有效的药物之一,能改善患者的血凝状态。
Objective: To observe the clinical efficacy of Maixnekang capsule in reconvalescents of cerebral infarction and its impact on coagulation function. Method: One hundred and twenty cases of reconvalescents of cerebral infarction were randomly divided into treatment and control groups. The 50 cases in the control group were provided with conventional therapy, while the 70 cases in the treatment group were provided with the combination of conventional therapy and Maixuekang capsule for 3 months. Their neurological function and prothrombin time (PT), activated partial thromboplastin time (AFFF) clotting enzyme time (Tr), fibrinogen (Fib) were measured before and after treatment. Result: After the treatment, PT, AFFF and TF were prolonged compared with those before the treatment in the treatment group (P 〈 0. 05), whereas Fib, neurological deficit scores decreased (P 〈 0. 01 ) and significantly different from the control group (P 〈 0. 05). Conclusion: Maixuekang capsule is among safe and effective drugs in treatment of reconvalescents of cerebral infarction, and can improve the patient's coagulation state.
出处
《中国中药杂志》
CAS
CSCD
北大核心
2012年第23期3667-3668,共2页
China Journal of Chinese Materia Medica
关键词
脉血康胶囊
脑梗死
凝血功能
Maixuekang capsule
cerebral infarction
coagulation function