摘要
综述了骨髓相关细胞向骨、软骨、肺、脑大小胶质细胞、骨骼肌、肝及血管内皮细胞等转化,神经干细胞和肌肉间叶细胞向造血细胞转化的研究进展。列举了干细胞可塑性研究的重要价值。
Recent reports have suggested that some ostensibly tissue-specific progenitors may have differentiation potential outside of their tissue of origin, that is to say stem cells derived from adult tissues may retain a previously unrecognized degree of plasticity. After bone marrow transplantation, donor-derived cells may be transformed to bone, cartilage, lung, astroglia in the brain, skeletal muscle, live and vascular endothelial cells, etc. On the contrary, neural stem cells and skeletal muscle cells could repopulate the hematopoietic cells. This paper reviewed these achievements and made an evaluation in the further research.
出处
《中国科学基金》
CSCD
2000年第4期193-196,共4页
Bulletin of National Natural Science Foundation of China
