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人肝细胞癌抑癌基因PTEN的缺失和突变分析 被引量:5

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出处 《中华肿瘤杂志》 CAS CSCD 北大核心 2000年第2期128-128,共1页 Chinese Journal of Oncology
基金 国家教委博士点基金 卫生部基金 上海市教委重点学科项目
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参考文献1

  • 1Li J,Science,1997年,275卷,1943页

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  • 1万小云,石一复,李娟清.PTEN基因对子宫内膜癌细胞生长的抑制作用[J].中华肿瘤杂志,2004,26(5):275-278. 被引量:7
  • 2Chu EC, Tarnawski AS. PTEN regulatory functions in tumor suppression and cell biology. Med Sci Monit, 2004, 10: RA235-241.
  • 3Lee C, Kim JS, Waldman T. PTEN gene targeting reveals a radiation-induced size checkpoint in human cancer cells. Cancer Res,2004, 64:6906-6914.
  • 4Saito Y, Swanson X, Mhashilkar AM, et al. Adenovirus-mediated transfer of the PTEN gene inhibits human colorectal cancer growth invitro and in vivo. Gene Ther, 2003, 10:1961-1969.
  • 5Shin Lee J, Seok Kim H, Bok Kim Y, et al. Expression of PTEN in renal cell carcinoma and its relation to tumor behavior and growth. J Surg Oncol, 2003, 84 : 166-172.
  • 6DeGraffenried LA, Fulcher L,Friedrichs WE, et al. Reduced PTEN expression in breast cancer cells confers susceptibility to inhibitors of the PI3 kinase/Akt pathway. Ann Oncol, 2004. 15,1510-1516.
  • 7Cantley LC. The phosphoinositide 3-Kinase pathway. Science,2002, 296 : 1655-1657.
  • 8Poetsch M, Dittberner T, Woenckhaus C. PTEN/MMAC1 in malignant melanoma and its importance for tumor progression[J]. Cancer Genet Cytogenet, 2001;125(1):21-26.
  • 9Freeman DJ, Li AG, Wei G. PTEN tumor suppressor regulates p53 protein levels and activity through phosphatase-dependent and -independent mechanisms[J]. Cancer Cell, 2003; 3(2): 117-130.
  • 10Lu DD, Zhang XR, Cao XR. Expression and significance of new tumor suppressor gene PTEN in primary liver cancer[J]. J Cell Mol Med, 2003;7(1):67-71.

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