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儿童颅咽管瘤189例临床分析 被引量:19

Pathological changes and protection of hypothalamus in pediatric craniopharyngioma
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摘要 目的 探讨儿童颅咽管瘤的病理特点以及手术切除和下丘脑损害的防治。方法 对189例儿童颅咽管瘤的CT、MRI影像学资料、手术所见及术后病理等进行分析。结果  189例中 ,囊性瘤体 187例 (98.9% ) ,其中钙化 176例 (93.1% ) ,实性瘤 2例 (1.1% ) ;牙釉质型颅咽管瘤 188例(99 5 % ) ,鳞状上皮乳头型 1例。肿瘤与下丘脑间有胶质增生层。生长方向有 :鞍内型 ,柄后型 ,柄前 视交叉型 ,视交叉前型 ,柄侧型。结论 儿童颅咽管瘤主要以囊性伴钙化为其病理特点 ,肿瘤与下丘脑、垂体柄的关系、以及保护这些重要结构是决定能否全切除肿瘤的重要因素。 Objective To understand the pathological changes of pediatric craniopharyngiomas so as to analyze its diagnosis, operative strategy and to prevent the damage of hypothalamus. Methods 189 cases of pediatric craniopharyngiomas treated from 1990 to 1998 were reviewed and analyzed via their CT, MRI, and surgery. Results 187 cases (98.9%) were cystic tumors, including 176 with calcification (93.1%); two cases were solid tumors (1.1%), and calcification occurred in only one. A gliosis layer between the wall of tumor and the hypothalamus was seen. Conclusion Cystic change and calcification are the pathological features of pediatric craniopharyngiomas. There are some special relations between the tumors and stalk. These are the bases for total removal of pediatric craniopharyngiomas.
出处 《中华医学杂志》 CAS CSCD 北大核心 2000年第4期280-282,共3页 National Medical Journal of China
基金 北京市科技新星基金
关键词 颅咽管瘤 下丘脑 儿童 诊断 治疗 临床分析 Craniopharyngioma Hypothalamus
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  • 1Wen D Y,Br J Neurosurg,1992年,6期,467页

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