摘要
为探讨剖腹与腹腔镜胆囊切除术 2种方法对高血压合并胆囊疾病患者血中内皮素和 C反应蛋白的影响 ,比较两种方法对机体损伤的程度及安全性 ,选择行剖腹胆囊切除术高血压患者 15例 ,腹腔镜胆囊切除术高血压患者 15例 ,无高血压腹腔镜胆囊切除术患者 15例 ,分别于术前、术中、术后 3h,12 h,2 4h抽取静脉血检测内皮素、C反应蛋白含量并进行比较。结果表明 :剖腹胆囊切除术高血压患者血中内皮素术中、术后含量明显高于腹腔镜胆囊切除术患者 (P<0 .0 1) ,C反应蛋白于术后 12 h明显高于腹腔镜胆囊切除术高血压患者。研究表明腹腔镜胆囊切除术刺激小 ,对高血压患者较为安全。
The effect of laparoscopy cholecystectomy (LC) and open cholecystectomy (OC) on the plasma contents of endothelin (ET) and C reactive protein (CRP) in the patients with hypertension was investigaed. The concentrations of ET and CRP were determined in the blood samples before and during operation, 3, 12, 24 h after operation in the hypertention patients undergoing OC (OC group, n =15), hypertension patients undergoing LC (LC1 group, n =15), and the non hypertension patients undergoing LC (LC2 group, n =15). The levels of ET were significantly increased during operation in the three groups and those in OC group were higher than in LC1 and LC2 groups ( P <0.01). CRP was significantly increased 3 h after operation in the three groups and the levels in OC group were higher than in LC1 and LC2 groups ( P <0.01), but no difference in CRP level between LC1 and LC2 groups was found. It was indicated that LC was safer to the patients with hypertension than OC.
出处
《同济医科大学学报》
CSCD
2000年第2期138-139,142,共3页
Acta Universitatis Medicinae Tongji
基金
国家自然科学基金!资助项目 (No. 39770 72 4)
