摘要
目的 超选择性肝动脉插管技术 ,化疗及栓塞联合治疗巨大型肝血管瘤的疗效观察。方法 采用Seldinger经皮股动脉穿刺插管法 ,在引导导丝的导向下 ,导管超选择至 2~ 3级肝动脉内 ,超选困难者 ,采用SP超微同轴导管 ,直到最接近肿瘤的主供血动脉 ;灌注平阳霉素 8~ 16mg ,缓慢推注鱼肝油酸钠与超液状碘油混合硬化栓塞剂。结果 本组对 11例巨大型肝血管瘤治疗后临床症状消失 ,有效率 10 0 % ,治疗后肿瘤内皮细胞变性、萎缩、退化 ,微血管损害破坏 ,纤维化 ,复查B超及CT肿瘤平均缩小 5 15cm× 8 95cm ,术后随访 16个月以上均健在 ,未见肿瘤复发。结论 超选择性肝动脉插管治疗巨大型肝血管瘤操作简便 ,损伤性小 。
Objective To observe the treatment of huge cavernous hemangioma of the liver with hepatic artery embolizations and chemotherapy using the method of supra selective hepatic artery catheterization.Methods The catheter was selected closely into tumors via femoral artery.Infused with Pingyangmycin 8 16mg,and injected slowly with Natriimorrhuatis and lipiodol ultra fluide. Results After treatment,the clinical symptoms were disappear in all 11 patients,tumors endothilial celll degeneration,withdraw,microvascular destruction and fibrosis.The mean dimension of tumors were 5 15×8 15cm.Follow up 16 months,patients are still alive and no recurrence of tumors. Conclusion The supra selective hepatic artery catheterization are simple,miniinjury,safe and effective method in the treatment of huge hepatic cavernous hemangioma.
出处
《肿瘤防治研究》
CAS
CSCD
北大核心
2000年第2期146-147,共2页
Cancer Research on Prevention and Treatment