摘要
目的修订暖宫七味丸的质量标准。方法采用显微鉴别方法,鉴别暖宫七味丸中豆蔻、天冬、肉豆蔻、沉香、手掌参及丁香;采用GC法,鉴别暖宫七味丸中豆蔻的主成分桉油精;采用HPLC法,测定暖宫七味丸的总丁香酚含量。结果显微鉴别及气相色谱鉴别专属性强。含量测定丁香酚线性范围为0.08560～3.264μg;样品的平均加样回收率为95.87%(n=6)。结论此方法简便、准确,重复性好,可作为暖宫七味丸的质量控制方法。
Objective To establish a method for quality control of Nuangong Qiwei Pill.Methods Microscopical identification method was used to analyze the microscopical characteristics of Nuangong Qiwei Pill;GC was used for the qualitative analysis of cineole,and HPLC was used for eugenol.Results Microscopical and GC methods for the assay of Nuangong Qiwei Pill were established and had good specificity.For HPLC,eugenol showed a good linear range of 0.08560-3.264 μg;the average recovery was 95.87%（n=6）.Conclusion The three methods mentioned above are all simple,accurate with good reproducibility and are applicable for the quality control of Nuangong Qiwei Pill.
出处
《中国药事》
CAS
2012年第10期1119-1121,1146,共4页
Chinese Pharmaceutical Affairs
基金
国家药典委员会2010年标准提高工作课题-暖宫七味丸质量标准研究(编号164)
关键词
暖宫七味丸
质量标准
显微鉴别
豆蔻
天冬
肉豆蔻
沉香
手掌参
丁香
气相色谱
高效液相色谱
桉油精
丁香酚
Nuangong Qiwei Pill
quality control
microscopical identification
Fructus Ammomi Rotundus
Radix Asparagi
nutmeg
Chinese eaglewood
gymnadnia conopsear broyn
clove
GC
HPLC
cineole
eugenol
