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脑损害患者的高级功能障碍与P_(300)对比研究 被引量:2

A Comparative Study of Advanced Nervous Disorder with P_(300) in Brain Damaged Patients
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摘要 对 6 8例不同病因的脑损害患者进行智商 (IQ)、记忆商 (MQ)、失认症及P30 0 检查 .其中脑梗塞34例、帕金森病 18例、多发性硬化 16例 ,并与 51例年龄、性别和利手相匹配的正常人比较 .结果 :脑损害各组患者的N2 及P3波峰潜伏期 (PL)较对照组显著延长 (P <0 0 1) ,P3波幅显著降低 (P <0 0 5) .IQ ,MQ与N2 及P3PL呈显著负相关 (P <0 0 1) ,图形认知、分解图形、重复认知及重复指认与P3PL显著负相关 ,P3波幅与图形认知显著负相关 .结果提示 :各组脑损害患者均存在不同程度的认知功能障碍 .P3PL是较为敏感的指标 . We examinated IQ,MQ,Agnosia and P 300 of 68 patients damaged in brain with different pathogeny. These cases include 34 cerebral infarction,18 Parkinson Disease,16 multiple sclerosis and they were compared with 51 normal people who were matched on age,sex and handedness. Result: PL in N 2 and P 300 of brain damaged group was significantly longer than that of control group ( P <0 01),and amplitude of P 3 was significantly decreased ( P <0 05).IQ,MQ and PL of N 2 and P 3 showed significantly negative correlation ( P <0 01).Drawing recognition,decomposing drawing,repeat recognition and repeat indication compared with P 3PL were significantly negative correlation and amplitude of P 3 showed significantly negative correlation with drawing cognition. The result suggests that cognition disorders are different in brain damaged patients. And P 3PL is a sensitive indicatrix.
出处 《昆明医学院学报》 2000年第1期73-75,共3页 Journal of Kunming Medical College
基金 云南省青年科学基金!95C137Q
关键词 脑梗塞 震颤性麻痹 多发性硬化 事件相关电位 Cerebral infarction Parkinson Disease Multiplesclerosis Event relatived potential Intellegence Recognition Memory
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