摘要
目的:探讨临床药师在重症感染病例救治中的作用。方法:临床药师通过参与神经外科1例肺部及中枢神经系统感染病例的会诊工作,根据患者临床表现及影像学特点考虑为混合感染,并结合患者的肝肾功能为患者制订个体化的抗感染方案:亚胺培南/西司他丁钠1g,ivgtt,tid;左氧氟沙星0.6g,ivgtt,qd;万古霉素0.5g,ivgtt,bid;伊曲康唑0.2g,ivgtt,bid。结果:采用上述治疗方案20d后,患者体温、血象恢复正常,2次脑脊液培养未见细菌生长;胸部CT提示肺部炎症明显吸收,双侧胸腔积液明显减少,与前比较明显好转。感染基本控制,转至康复理疗科进行理疗。结论:临床药师参与临床治疗,有利于提高临床治疗水平,促进合理用药。
OBJECTIVE： To investigate the role of clinical pharmacists in the treatment of severe infection. METHODS： Clinical pharmacists took part in the consultations of a case of lung and central nervous system infection in neurosurgery department and considered it as mixed infection according to clinical manifestation and imaging feature, and provided individualized dosage regimen on the basis of hepatic and renal function of patient： imipenem/cilastatin sodium 1 g, ivgtt, tid; levofloxacin 0.6 g, ivgtt, qd; vancomycin 0.5 g, ivgtt, bid; itraconazole 0.2 g, ivgtt, bid. RESULTS： After 20 days of above therapy, body temperature and hemogram of patient returned normal, and there was no growth of bacteria in twice of cerebrospinal fluid culture. CT manifestation of chest pointed out obvious absorption of pulmonary inflammation and pleural effusion on both sides decreased significantly, which were better than before. Infection were controlled basically and then the patient was transferred to rehabilitation and physical therapy section to receive physiotherapy. CONCLUSION： The participation of clinical pharmacists in clinical treatment can improve therapeutic level and promote rational drug use.
出处
《中国药房》
CAS
CSCD
2012年第46期4406-4408,共3页
China Pharmacy
关键词
临床药师
肺部感染
中枢神经系统感染
会诊
合理用药
Clinical pharmacists
Lung infection
Central nervous system infection
Consultations
Rational drug use
