摘要
目的:了解我院药品不良反应(ADR)发生的特点及规律,为临床合理用药提供参考。方法:收集我院2009-2011年上报的353例ADR报告,按患者性别、年龄、给药途径、涉及药品种类、累及器官或系统及临床表现等进行统计、分析。结果:353例ADR报告中,60岁以上患者居首位,占30.59%;女性患者较男性多,分别占56.94%和43.06%;引发ADR的给药途径以静脉滴注给药为主,占79.05%;由抗微生物药引发的ADR最多,占49.29%;ADR累及器官或系统以皮肤及其附件损害最常见,占46.74%。结论:医院应重视ADR的监测工作,尤其要重视合理使用抗菌药物,关注ADR的易发人群,以减少ADR的发生。
OBJECTIVE： To investigate the characteristics and regulations of adverse drug reaction （ADR） in our hospital, and to provide reference for rational drug use in the clinic. METHODS： 353 ADR reports collected from our hospital from 2009 to 2011 were analyzed statistically in terms of patients’ age,gender,route of administration, drug variety, organs or systems involved in ADR and clinical manifestations, etc. RESULTS： Of total 353 cases, most were senile patients aged above 60 years old, accounting for 30.59%; female cases were more than male cases, accounting for 56.94% and 43.06%;most of ADR were induced by intravenous dripping, accounting for 79.05%; most of ADR were induced by antimicrobial drugs, accounting for 49.29%; the most common clinical manifestations were the damage of skin and appendants, accounting for 46.74%. CONCLUSION： Importance should be attached to ADR report and monitoring, especially rational use of antibiotics. Attention to people prone to occur adverse reactions should be emphasized to reduce the occurrence of ADR.
出处
《中国药房》
CAS
CSCD
2012年第46期4387-4390,共4页
China Pharmacy
关键词
药品不良反应
分析
合理用药
Adverse drug reaction
Analysis
Rational use of drugs
