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嗜酸性粒细胞凋亡与鼻息肉发病的研究 被引量:1

The Resarch of Eosinophil Apptosis and Nasal Polyps
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摘要 目的考察嗜酸性粒细胞在鼻腔正常下鼻甲黏膜及鼻息肉标本中的分布情况及凋亡情况,研究嗜酸性粒细胞凋亡与鼻息肉发病间的关系。方法通过流式细胞仪观察鼻息肉组(A组,21例)和对照组(B组,7例)嗜酸性粒细胞分布情况,AnnexinV-PE染色后,在流式细胞仪下检测嗜酸性粒细胞凋亡情况。结果A组嗜酸性粒细胞个数(12.83±5.20)明显高于B组(4.38±1.99)(P<0.05);A组凋亡的嗜酸性粒细胞比例(0.81±0.15)%明显低于B组(24.73±1.22)%(P<0.05)。结论嗜酸性粒细胞的浸润及凋亡受抑制可能在鼻息肉的发生、发展中具有重要作用。
出处 《现代诊断与治疗》 CAS 2012年第9期1386-1387,共2页 Modern Diagnosis and Treatment
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