摘要
目的探讨儿童肠道病毒71型(EV71)感染并发肺出血的危险因素。方法回顾性分析203例EV71感染重型手足口病患儿的临床资料,203例患儿中伴肺出血38例,探讨EV71感染并发肺出血的危险因素。结果单因素分析发现,呕吐、嗜睡、肢体抖动、心动过速或过缓、血压升高或降低、静脉血糖升高及外周血白细胞计数异常7项指标,在并发肺出血和未并发肺出血患儿之间的差异有统计学意义(P<0.05)。多因素Logistic回归分析显示,血压、呕吐、肢体抖动、静脉血糖水平、嗜睡5种因素是EV71感染合并肺出血的危险因素。结论 EV71感染患儿出现嗜睡、肢体抖动、血压升高或降低、静脉血糖升高、呕吐时,并发肺出血的可能性较大,应严密监测,及早干预。
Objective To explore the risk factors of pulmonary hemorrhage in enterovirus 71 （EV71） infected chil- dren. Methods The clinical information of 203 children with severe hand-foot-mouth disease （HFMD） affected with EV71 were analyzed retrospectively and the risk factors were explored. Pulmonary hemorrhage was present in 38 children. Results Single factor analysis found that there were significant differences between patients with pulmonary hemorrhage and those without pulmonary hemorrhage in 7 indexes including cmesis, drowsiness, limb shaking, brady and tachycardia, hyperten- sion or hypotension, venous blood glucose increasing, peripheral white blood cell counting （P〈0.05）. Multiple factor Logistic analysis indicated blood pressure, emesis, limb shaking, venous blood sugar level and drowsiness were the risk factors of EV71 infection with pulmonary hemorrhage. Conclusions It may increase the possibility of occurrence of pulmonary hemorrhage when the EV71 infected children present drowsiness, limb shaking, hypertension or hypotension, elevated venous blood sugar and vomiting. The close observation and early intervention are critical for treatment of this disease.
出处
《临床儿科杂志》
CAS
CSCD
北大核心
2012年第11期1044-1046,共3页
Journal of Clinical Pediatrics
