摘要
目的 :探讨白血病患者外周血T淋巴细胞亚群和可溶性白细胞介素 2受体 (sIL 2R)的变化。方法 :分别应用单克隆抗体技术和酶联吸附试验检测 31例白血病患者外周血T淋巴细胞亚群和sIL 2R水平 ,并以 35名正常人作对照。结果 :白血病患者外周血CD3+ 、CD4+ 细胞数低于正常人 ,CD8+ 细胞数高于正常人 (P <0 .0 1) ,CD4+ /CD8+ 比值下降 (P <0 .0 1)。血清sIL 2R活性明显高于正常人 (P <0 .0 1)。结论 :测定白血病患者外周血T淋巴细胞亚群和sIL 2R水平对了解患者的免疫状态具有一定的临床价值。
?Objective:To study the changes of serum sIL 2R and T lymphocyte subgroup in patients with leukemia.Methods:Serum levels of sIL 2R and T lymphocyte subgroup in 31 leukemia patients and 35 healthy persons as control were determined by Elisa and monoclone of antibody technique.Results:The T lymphocytes of subgroup CD3\++,CD4\++ and CD4\++/CD8\++ in periferal blood were lower than those in normal controls( P < 0.01 ). CD8\++ and sIL 2R were higher than those in normal controls( P <0.01).Conclusions:The results shows that the detection of T lymphocyte subgroup and sIL 2R has important value in understanding the immune state of leukemia patients .
出处
《蚌埠医学院学报》
CAS
2000年第2期142-143,共2页
Journal of Bengbu Medical College
