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CYFRA21-1对非小细胞肺癌胸腔积液的诊断价值 被引量:4

The value of CYFRA 21-1 in diagnosis of non-small cell lung cancer with pleural effusion.
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摘要 目的 探讨非小细胞肺癌标记物 (CYFRA 2 1- 1)对非小细胞肺癌 (NSCLC)胸腔积液的诊断价值。方法 用放免法测定了非小细胞肺癌 ,小细胞肺癌 (SCLC)及结核性胸膜炎的胸腔积液CYFRA 2 1- 1水平。结果 非小细胞肺癌胸腔积液的CYFRA 2 1- 1水平 ,无论细胞学阳性或阴性 ,均显著高于小细胞肺癌及结核性胸膜炎的胸腔积液组 (P <0 0 1)。结论 检测胸腔积液CYFRA 2 1- Objective To investigate the value of testing CYFRA 21-1 level in diagnosis of non-small cell lung cancer(NSCLC)combined with pleural effusion.Methods By means of immunoradiometric assay,measure the level of CYFRA 21-1 in patients with NSCLC,small cell lung cancer(SCLC)and tuberculosis combined with pleural effusion.Results The level of CYFRA 21-1 in patients with pleural effusion of NSCLC was significantly higher than patients in contrast groups(P<0\^01)either pathological positive or negative.Conclusion Testing the level of CYFRA 21-1 in pleural effusion plays an important role in diagnosis of NSCLC.?fibrillation and discuss the problems confronted in this procedure.Methods 5 patients with focus atrial fibrillation accepted electrophysiologic study and radiofrequency ablation,1 guided by X-ray combining intracardiac mapping,the other guided by intracardiac echocardiography.Efficacy of the procedure,time for operation and X-ray exposure were compared.Results (1)Of the 5 patients,3 got immediately successful results,2 failed to the procedure.Atrial fibrillation recovered in 24 hours after ablation in 1 patient who has got success immediately.Delayed success occurred in 1 patient without relapse 3 months later.(2)Compared with the X-ray guiding method,intracardiac echocardiography can clearly show the interatrial septum and pulmonary vein.These properties are helpful to guiding the puncture septum and ablation around the ostium of pulmonary vein accurately,and also can save operative time and decrease the exposeure to the X-ray.(3)The two main difficulties encountered when searching for this type of focal source,however,are patients with too few atrial premeature beats and no episode of atrial fibrillation initiated by one ectopic beat at base state and isoprotenol infusion combined with burst atrial pacing.(4)1 patient who accepted intracardiac echocardiography guiding method suffered a tamponade after advancing the transseptum sheath.Echocardiography combined with X-ray may be helpful to avoid this complication.Conclusion Radiofrequency ablation is a hopeful method to cure the focus atrial fibrillation, intracardiac echocardiography is important to direct the ablation catheter accurately.At present,selecting proper patients for this procedure is very important because some obstacles lie in the procedure and need to be solved.
出处 《中国实用内科杂志》 CAS CSCD 北大核心 2000年第3期144-145,共2页 Chinese Journal of Practical Internal Medicine
关键词 非小细胞肺癌 胸腔积液 诊断 CYERA21-1 Non-small cell lung cancer(NSCLC)\ CYFRA 21-1\ Pleural effusion
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