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血浆同型半胱氨酸水平与颈部动脉粥样硬化患者脑梗死复发的相关性研究 被引量：7

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摘要 目的探讨血浆同型半胱氨酸(homocysteine,Hcy)水平与颈动脉粥样硬化患者复发性脑梗死的关系。方法颈动脉粥样硬化患者160例,根据脑梗死发生次数,分为脑梗死复发组52例,脑梗死初发组54例,无脑梗死或脑出血对照组54例;检测并比较各组血浆Hcy的水平及颈动脉粥样硬化斑块类型。结果脑梗死复发组及初发组血浆Hcy水平和高同型半胱氨酸血症(HHcy)发生率均显著高于对照组(P<0.01),脑梗死复发组血浆Hcy水平和HHcy发生率亦显著高于脑梗死初发组(P<0.05);脑梗死复发组易损斑块发生率显著高于脑梗死初发组(88.5%比64.8%,P<0.05);脑梗死组检出易损斑块患者的血浆Hcy水平显著高于硬斑块患者[(28.96±7.01)μmol/L比(23.56±6.98)μmol/L,P<0.05]。结论血浆Hcy水平与颈动脉粥样硬化患者易损斑块的形成及脑梗死的复发可能相关。
作者 顾媛媛 冯来会
机构地区 郑州人民医院神经内科
出处 《中国实用神经疾病杂志》 2012年第20期24-26,共3页 Chinese Journal of Practical Nervous Diseases
关键词 脑梗死 颈动脉粥样硬化 复发 同型半胱氨酸
分类号 R743.33 [医药卫生—神经病学与精神病学]
  • 相关文献

参考文献14

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共引文献786

同被引文献50

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引证文献7

二级引证文献41

中国实用神经疾病杂志
2012年 第20期

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