摘要
目的 探讨外科治疗对Ⅳa期肝癌的效果。方法 回顾性分析 1989～ 1998年间 2 7例Ⅳa期肝癌患者 ,其中手术切除 19例 (切除组 ) ,减瘤术加术中无水酒精注射 8例 (减瘤术组 )。术中行B超检查 ,不遗漏任何一个病灶 ,尽量切除所有瘤结节 ,残留结节实施B超引导下的无水酒精注射术。将减瘤术置于多方法序贯治疗当中。结果 全部 2 7例患者的 1,2 ,3年生存率分别为 71 4%、5 5 6 %和 7 7%。切除组和减瘤术组 1,2 ,3年生存率分别为 73.3%、5 8.3%、10 .0 %和 6 6 .7%、5 0 .0 %、0 (P >0 .0 5 )。术后并发症发生率为 2 2 0 % ,无手术死亡和住院死亡。结论 Ⅳa期肝癌实施外科治疗 ,包括切除术。
Objective To study the result of surgical treatment of patients with stage Ⅳa primary liver carcinoma (PLC).Methods Twentyseven patients with stage Ⅳa PLC treated in 1989 1998 were retrospectively studied. The patients could be divided into 2 groups: (1) The resected group(19 cases) and (2) cytoreductive group (8 cases). Intra operative B ultrasound was used to prevent missing of any tumor nodules. Unresectable residual nodules were treated by ethanol injection. Multidisciplinary treatment was given in the perioperative period.Results The overall 1 , 2 and 3 year survival rate of the 27 patients was 71.4%,55.6% and 7.7% respectively. The 1 , 2 and 3 year survival rate of the resected and cytoredudctive group of patients was 73.3%, 58.3%,10.0% and 66.7%, 50.0%, 0% ( P >0.05) respectively. Complications occurred in 22.0% of the treated patients. There was no operative and hospitalization mortality.Conclusions Surgical resection or cytoreductive operation with adjuvant therapy is effective as the first choice of treatment for stage Ⅳa PLC.
出处
《中华肿瘤杂志》
CAS
CSCD
北大核心
2000年第3期252-254,共3页
Chinese Journal of Oncology
关键词
肝肿瘤
肝切除术
生存率
外科手术
Liver neoplasms/surgery
Hepatectomy
Survival rate
