期刊文献+

鼠神经生长因子治疗突发性耳聋疗效分析 被引量:20

Curative effect of mouse nerve growth factor for sudden deafness
暂未订购
导出
摘要 目的观察鼠神经生长因子对突发性耳聋的疗效。方法 187例病人分为治疗组102例,给予常规治疗加鼠神经生长因子肌内注射;对照组85例,给予静滴,营养神经药物以及口服维生素等常规治疗改善循环,疗程均为14d,观察听力恢复情况。结果治疗组总有效率85.3%(87/102),对照组总有效率72.9%(62/85),差异有统计学意义(P<0.05)。结论鼠神经生长因子治疗突发性耳聋安全、有效,无明显不良反应。 Objective To evaluate the curative effect of mouse nerve growth factor for sudden deafness.Methods Totally 187 cases of sudden deafness were divided two groups: treatment group(102 cases with 108 ears) were treated by mouse nerve growth factor and routine therapy;control group(85 cases with 89 ears) were treated by routine therapy(the medicine of relaxing blood vessels and protecting nerves injection and oral Vitamin),the recruitment of hearing after 14-day treatment was observed.Results The effective rate of treatment group was 85.3%,which was significantly higher than that of control group(72.9%,P0.05).Conclusion The mouse nerve growth factor was safe and effective for sudden deafness without side effect.
出处 《中国实用神经疾病杂志》 2012年第21期17-18,共2页 Chinese Journal of Practical Nervous Diseases
关键词 突发性耳聋 鼠神经生长因子 Sudden deafness Mouse nerve growth factor
  • 相关文献

参考文献5

  • 1突发性聋的诊断和治疗指南(2005年,济南)[J].中华耳鼻咽喉头颈外科杂志,2006,41(8):569-569. 被引量:871
  • 2Hu Z,Vlfendall M,Vlivius NP. NGF Stimulates extensive neu- rite outgrowth from implanted dorsal root ganglian neurons fol- lowing transplantation into the adult rat inner ear[J]. Neurobi- ol Dis,2005,18(1) :184-192.
  • 3阮芳铭,王海明,高文元,季红光,肖建平,王福俤,刘长云,潘祥福,张麟.神经生长因子减轻噪声性阈移的透射电镜观察[J].中华耳鼻咽喉科杂志,2000,35(4):267-270. 被引量:15
  • 4Shoji F, Miller AL, Mitchell A, et al. Differenal protective effects of naurotrophinth accennation of noise-induced hair cell loss[J]. HearRrs,2000,146: 134-142.
  • 5Shah SB,Gladstone H B,Willians H, et al. An extended study: protective effects of nerve growth factor in neomycin-induced auditory neural degeneration[J]. Am J Otol, 2001,16 : 310-314.

二级参考文献4

共引文献883

同被引文献224

引证文献20

二级引证文献121

相关作者

内容加载中请稍等...

相关机构

内容加载中请稍等...

相关主题

内容加载中请稍等...

浏览历史

内容加载中请稍等...
;
使用帮助 返回顶部