摘要
为探讨母亲血铅对其婴幼儿智力和精神运动发育的影响。选择在沈阳市 3个区居住的新婚夫妇 ,对其跟踪调查 ,采集并测定孕前、孕中、产前妇女的静脉血血铅浓度和脐带血血铅浓度 ,并对小孩出生后的不同时期测量的智力发育指数(MDI)和精神运动发育指数 (PDI)与其母亲的血铅浓度和脐带血铅浓度进行相关分析和逐步回归分析。结果表明 :2 3 3例新婚妇女孕前时期的血铅浓度为 11 5 8μg/dl;70例孕早血和 66例产前血及 76例脐带血的平均铅水平分别为 9 2 3 μg/dl、8 2 8μg/dl、7 70 μg/dl。对 6～ 3 0个月的婴幼儿每 6个月测定一次MDI的均数值分别 为 10 1 86、10 9 0 6、10 4 0 0、10 7 5 5、113 4 5 ;PDI的均数值分别为 10 4 5 1、10 8 2 5、10 5 61、116 89、114 0 7。婴幼儿不同时期的MDI和PDI与母亲不同时期的血铅水平和脐带血铅水平呈负相关。结论是高血铅暴露对婴幼儿的智商产生不利影响。
To study the effects of mother’s blood lead on new born baby,we followed up newly-married women,collecting their blood before pregnancy,mid-pregnancy,right before giving birth, and blood from umbilical cord.A series of IQ tests for MDI and PDI were followed since 6 months of the baby’s age with an interval of 6 months Step-wise regression and correlation between blood lead levels of different times and the IQ scores of the baby at different ages were analyzed.Results showed that the log mean levels of blood lead before pregnancy,in mid-pregnancy, riglht before giving birth, and from umbilical cord were 11.58μg/dl,9.23μg/dl,8.28μg/dl and 7.70μg/dl respectively. The baby’s average IQ scores((MDI+PDl)/2) at 6,12,18,24,and 30 months of age were 103.19,108.66,104.81,112.22,113.76 respectively.Negative correlation between mother’s blood lead levels and baby’s IQ scores were observed.Conclusion is that high level of mother”s blood lead has adverse effects on baby's development in intelligence and genius movement.
出处
《中国公共卫生》
CAS
CSCD
北大核心
2000年第5期390-391,共2页
Chinese Journal of Public Health
