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降钙素原在肝移植术后感染患者中的应用价值 被引量:2

Application value of procalcitonin on infection in patients after liver transplantation operation
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摘要 目的探讨血清中降钙素原(PCT)在肝移植术后感染患者中的应用价值。方法检测32例肝移植术后感染患者血清PCT和C-反应蛋白(CRP)水平,并与肝移植术后未感染患者及健康体检者(对照组)进行比较。结果感染组患者血清PCT水平高于非感染组及对照组(P<0.01),非感染组高于对照组(P<0.05);而感染组与非感染组CRP水平比较差异无统计学意义(P>0.05),但均高于对照组(P<0.05),感染组恢复期血清PCT水平下降,但仍高于对照组(P<0.05)。结论血清降钙素原水平检测有助于肝移植术后感染的早期诊断及鉴别诊断,并可作为判断预后的指标。 Objective To investigate the application value of plasma procalcitonin(PCT) on infection in patients after liver transplantation operation.Methods The levels of plasma PCT and C-reactive protein(CRP) in 32 patients with postoperative infection who underwent liver transplantation were detected and the levels were compared with patients without postoperative infection and healthy volunteer.Results The level of plasma PCT in postoperative infection group was significantly higher than that in without postoperative infection group and healthy volunteer group(P0.01),and the level of plasma PCT in without postoperative infection group was significantly higher than that in healthy volunteer group(P0.05).The levels of plasma CRP in postoperative infection group and without postoperative infection group were significantly higher than that in healthy volunteer group(P0.05),but there was no significant difference between postoperative infection group and without postoperative infection group(P0.05).The level of plasma PCT in postoperative infection group decreased during recovery phase,but it also was higher than that in healthy volunteer group(P0.05).Conclusion Detection of the plasma levels of PCT is benefitial for early diagnosis and differential diagnosis of infection after liver transplantation,and PCT can be used as an indicator of prognosis.
出处 《临床医学》 CAS 2012年第7期1-2,共2页 Clinical Medicine
关键词 肝移植 降钙素原 C-反应蛋白 感染 Liver transplantation Procalcitonin C-reactive protein Infection
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参考文献6

  • 1朱继业,高鹏骥,栗光明,朱凤雪,黄磊,王东,高杰,冷希圣.单中心565例肝移植病例分析[J].北京大学学报(医学版),2009,41(3):368-372. 被引量:4
  • 2Chen J,Wang Y,Shen Z,et al.Early diagnostic value of plasma PCT and BG assay for CRBSI after OLT[J].Transplant Proc,2011,43(5):1777-1779.
  • 3Perrakis A,Yedibela S,Schellerer V,et al.Procalcitonin in the setting of complicated postoperative course after liver transplantation[J].Transplant Proc,2010,42(10):4187-4190.
  • 4Jensen JU,Lundgren JD.Procalcitonin in liver transplant patients-yet another stone turned[J].Crit Care,2008,12(1):108.
  • 5Eyraud D,Ben Ayed S,Tanguy ML,et al.Procalcitonin in liver transplantation:are high levels due to donors or recipients[J] ?Crit Care,2008,12(4):R85.
  • 6Van den Broek MA,Olde Damink SW,Winkens B,et al.Procalcitonin as a prognostic marker for infectious complications in liver transplant recipients in an intensive care unit[J].Liver Transpl,2010,16(3):402-410.

二级参考文献16

  • 1朱继业.肝移植术后早期细菌感染的防治[J].中国实用外科杂志,2004,24(6):341-343. 被引量:25
  • 2高杰,朱凤雪,朱继业,栗光明,黄磊,王东,冷希圣.连续肾脏替代治疗在肝移植围手术期的应用[J].中华普通外科杂志,2005,20(6):359-361. 被引量:10
  • 3栗光明,朱继业,黄磊,刘沐云,王东,朱凤雪,高杰,冷希圣.肝移植术后胆管非吻合口狭窄的病因分析[J].中华普通外科杂志,2007,22(1):38-41. 被引量:9
  • 4Hanto DW,Fishbein TM,Pinson CW,et al.Liver and intestine transplantation:summary analysis,1994-2003[J].Am J Transplant,2005,5(4 Pt 2):916 -933.
  • 5Lerut J,Laterre PF,Roggen F,et al.Adult liver transplantation:UCL experience[J].Acta Gastroenlerol Belg,1999,62(3):306-318.
  • 6Mazzaferro V,Regalia E,Doci R,et al.Liver transplantation for the treatment of small hepatocellular carcinomas in patients with cirrhosis[J].N Engl J Med,1996,334(11):693 -699.
  • 7Bhattacharjya S,Bhattacharjya T,Quaglia A,et al.Liver transplantation in cirrhotic patients with small hepatocellular carcinoma:an analysis of pre-operative imaging,explant histology and prognostic histologic indicators[J].Dig Surg,2004,21 (2):152 -160.
  • 8Vivarelli M,Cucchetti A,La Barba G,et al.Liver transplantation for hepatocellular carcinoma under calcineurin inhibitors: reassessment of risk factors for tumor recurrence[J].Ann Surg,2008,248(5):857-862.
  • 9Anselmo DM,Ghobrial RM,Jung LC,et al.New era of liver transplantation for hepatitis B:a 17-year single-center experience[J].Ann Surg,2002,235(5):611 -620.
  • 10Marzano A,Gaia S,Ghisetti V,et al.Viral load at the time of liver transplantation and risk of hepatitis B virus recurrence[J].Liver Transpl,2005,11 (4):402 -429.

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