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丁苯酞氯化钠注射液治疗脑梗死的临床疗效 被引量:7

Efficacy of dl-3n-butylphthalide injection on cerebral infarction
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摘要 目的观察丁苯酞氯化钠注射液(恩必普注射液)治疗脑梗死(CI)的临床疗效。方法入院脑梗死患者予以肠溶阿司匹林100 mg,每晚1次;阿托伐他汀钙40 mg,每晚1次,同时进行高压氧和系统康复治疗。丁苯酞氯化钠注射液组患者同时使用丁苯酞氯化钠注射液25 mg静脉滴注,每12小时1次,连续使用14 d,通过ESS评分、Glasgow评分和NIHSS评分比较疗效。结果丁苯酞氯化钠注射液组在治疗中神经功能改善优于对照组,差异有统计学意义(P<0.05)。结论丁苯酞氯化钠注射液治疗脑梗死有效。 Objective To observe the clinical efficacy of dl-3n-butylphthalide injection(NBP)on cerebral infarction.Methods Patients with cerebral infarction were treated with enteric-coated aspirin 100 mg and atorvastatin calcium 40 mg together per-night,hyperbaric oxygen and systemic convalescent care were given at the same time.Patients in dl-3n-butylphthalide group were given 25 mg of NBP injection 2 times a day during the 14-day treatment in addition.The effects were compared by European stroke scale(ESS),National institutes of health stroke scale(NIHSS) and Glasgow coma scale.Results The neural function improvement of NBP injection group was supirior to that of control group,there was significant difference(P0.05).Conclusion NBP injection was effective for the treatment of cerebral infarction.
出处 《临床医学》 CAS 2012年第6期16-17,共2页 Clinical Medicine
关键词 丁苯酞 脑梗死 ESS评分 NIHSS评分 GLASGOW评分 Dl-3n-butylphthalide Cerebral infarction European stroke scale National institutes of health stroke scale Glasgow coma scale
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  • 1中华医学会神经病学分会脑血管病学组急性缺血性脑卒中诊治指南撰写组.中国急性缺血性脑卒中诊治指南2010[J].中国医学前沿杂志(电子版),2010,2(4):50-59. 被引量:1990
  • 2冯亦璞,胡盾,张丽英.丁基苯酞对小鼠全脑缺血的保护作用[J].药学学报,1995,30(10):741-744. 被引量:124
  • 3各类脑血管疾病诊断要点[J].中华神经科杂志,1996,29(6):379-380. 被引量:33089
  • 4脑卒中患者临床神经功能缺损程度评分标准(1995)[J].中华神经科杂志,1996,29(6):381-383. 被引量:15822
  • 5Elkind M S. Inflammatory markers and stroke[J]. Curr Cardiol Rep,2009,11(1) ;12-20.
  • 6Slevin M, Krupinski J, Badimon L. Controlling the angiogenic switch in developing atherosclerotic plaques: possible targets for therapeutic intervention[J]. J Angiogenes Res, 2009,21 (1) : 4.
  • 7Thompson A, Gao P, Orfei L, et al. Lipoprotein-associated phospholipase A(2) and risk of coronary disease, stroke, and mortality; collaborative analysis of 32 prospective studies [J]. Lancet, 2010,375 (9725) ..1536-1544.
  • 8Massot A, Pelegri D, Penalba A, et al. Lipoprotein-associated phospholipase A2 testing usefulness among patients with symptomatic intracranial atherosclerotie disease [J]. Atherosclerosis, 2011,218(1) ;181-187.
  • 9Wang X, Wang L, Huang Z, et al. Synthesis and biological evaluation of nitric oxide releasing derivatives of 6-amino-3-n butylphthalide as potential antiplatelet agents [J]. Bioorg Med Chem Lett, 2013,23 (7) ; 1985-1988.
  • 10舒勤奋,刘小利,姜寿峰,吴炯,金煜,倪娇娜.丁苯酞增强脑缺血耐受的实验研究[J].中国医院药学杂志,2008,28(15):1274-1277. 被引量:12

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