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静脉注射帕瑞昔布钠预防SLIPA喉罩引发咽喉不适的临床研究

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摘要 目的研究麻醉诱导前30min静脉注射帕瑞昔布钠减轻SLIPA喉罩引发全麻患者术后咽喉部不适的有效性。方法 120例ASAⅠ或Ⅱ级,择期全麻下手术的成年患者随机分为观察组和对照组,每组60例。Ⅰ组麻醉诱导前30min静脉注射4ml 0.9%氯化钠溶液,Ⅱ组麻醉诱导前30min静脉注射4ml(40mg)帕瑞昔布钠。对2组SLIPA喉罩放置时间、放置次数、拔出喉罩表面是否有血迹、术后咽喉部不适的发生率及不适程度等方面进行评价。结果 2组患者术后主要并发症均为咽痛,Ⅱ组患者咽痛发生率(25%)明显低于Ⅰ组(45%)(P<0.05),且其咽痛的VAS评分明显低于Ⅰ组患者(P<0.01)。结论麻醉诱导前30min静脉注射帕瑞昔布钠40 mg可降低SLIPA喉罩引发全麻患者术后咽喉部不适的发生率,且能减轻咽喉部不适的程度,值得临床推广应用。
出处 《河北医药》 CAS 2012年第20期3073-3074,共2页 Hebei Medical Journal
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参考文献10

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