摘要
目的探讨硝酸甘油静脉滴注治疗高血压急症的临床疗效及安全性。方法选择符合高血压急症的患者68例,按入院的先后顺序,随机分为观察组与对照组,每组34例。观察组用硝酸甘油10～20mg加入5%葡萄糖溶液250ml中,静脉滴注,10～20μg/min。对照组用硝普钠25～50mg加入5%葡萄糖溶液500ml中,避光,缓慢静滴,10～25μg/min。分别记录用药前后血压、心率及临床表现的变化。结果观察组有效率97.1%;对照组有效率94.4%,组间差异有统计学意义(p<0.05)。结论硝酸甘油静脉滴注治疗高血压急症具有起效快、操作方便、副作用少的特点,值得临床推广应用。
Objective To explore the clinical efficacy and safety of nitroglycerin intravenous drip on treatment of hypertensive emergencies. Methods By order of admission, 68 patients with hypertensive emergencies has randomly di- vided into observation group and control group （n= 34）. The observation group： nitroglycerin 10-20mg, 5% glucose solution 250ml, intravenous infusion, 10-20μg/min. Control group： 5% glucose solution in 500ml of sodium nitroprus- side 25-50mg, dark, slow intravenous infusion,10-25μg/min. Blood pressure, heart rate, and clinical manifestations of the changes were recorded before and after treatment. Results The effective rate of Observation group and control group were 97.6% and 97.4% （P〈0. 05）. Conclusion In treatment of hypertensive emergencies, nitroglycerin intrave- nous drip has efficience and is easy to operate with fewer side effects .
出处
《西部医学》
2012年第11期2142-2143,共2页
Medical Journal of West China
关键词
硝酸甘油
硝普钠
高血压急症
疗效观察
Nitroglycerin
Sodium nitroprusside
Hypertensive emergency
Clinical observation
