摘要
目的探讨早产儿高胆红素血症（下称高胆）患儿的阴离子隙（AG）变化，为治疗提供依据。方法测定94例高胆早产儿血清电解质、肾功能、肝功能，计算AG值，其中36例同时做动脉血气分析。结果高AG44例（46．81％），正常AG44例（46．81％），低AG6例（6．38％）。AG增高与血Na＋浓度成正比，与HCO3-呈反比。AG与血清尿素氮（BUN）、肌酐（Scr）无相关性。结论高胆早产儿高AG代谢性酸中毒发生率高，应常规测定血电解质、肾功能及动脉血气，计算AG值以指导治疗，以免盲目用碱纠酸。
Objective To investigate the changes of the anion gap（AG） in the premature suffered from hy- perbilirubinemia, to provide the basis for treatment. Methods The serum electrolyte, the renal function and the liver function in 94 premature babies suffered from hyperbilirubinemia were tested, and then calculated the value of AG, while the arterial blood gas analyses were done in 36 cases. Results 44 cases had high AG （46.81% ） ,44 cases had normal AG （46.81%） and 6 cases had low AG （6.38%）. The increase of AG was directly proportional to the con- centration of Na ＋ in blood, while was inversely proportion to the concentration of HCO3- . There was no close relation- ship between the AG and BUN, Scr in the serum. Conclusion The incidence rate of metabolic acidosis poisoning was high in premature suffered from hyperbilirubinemia with high AG, so the routine test of blood electrolyte, renal function and arterial blood gas should be done. Calculate the value of AG to guide the treatment, and to avoid correcting the acid by the alkali blindly.
出处
《中国基层医药》
CAS
2012年第22期3379-3380,共2页
Chinese Journal of Primary Medicine and Pharmacy
