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胸腔导管留置联合注射药物治疗结核性胸膜炎的探讨 被引量:12

胸腔导管留置联合注射药物治疗结核性胸膜炎的探讨
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摘要 目的探讨留置胸腔静脉导管,联合注射尿激酶和糖皮质激素治疗结核性胸膜炎的可行性及疗效。方法选择结核性胸膜炎患者随机分为治疗组:胸穿留置胸腔静脉导管并注入尿激酶+地塞米松;对照组A:留置胸腔静脉导管后只注射尿激酶;对照组B:留置胸腔静脉导管后只注射地塞米松。对比3组胸水消失时间、胸膜粘连以及胸膜肥厚的程度。结果胸水吸收时间3组无明显差异,治疗组胸膜粘连肥厚的患者较对照组明显减少且程度明显减轻(P<0.05)。结论胸腔静脉导管留置联合注射尿激酶和糖皮质激素,能有效的减少胸膜粘连和胸膜肥厚的发生。 Objective To observe the curative effect of intrapleural urokinase and glucocorticoids through venous catheter for tuberculous pleurisy. Methods Forty-two patients with tuberculous pleurisy were randomly divided into 3 groups: the patients in the treatment group were injected with urodinase and glucocorticoids through indwelling venous catheter intrapleurally each time. and the patients in the control group A were injected with urodinase only each firnc, the patients in the control group B were injected with glucocorticoids only each time. The other therapies in all groups were the same. Results There were no signifcant differences in the absorption duration of pleural effusion among the three groups (P〉0.05), the incidence Of pleural adhesion and thickening of pleura were significantly lower (P〈0.05) in the treatment group than those in the control groups. Conclusion Intrapleural urokinase and glucocortieoids through indwelling venous catheter can effective reduces pleural adlhesion and thickening of the pleura.
出处 《当代医学》 2012年第33期49-50,共2页 Contemporary Medicine
关键词 结核性胸膜炎 胸腔静脉导管 尿激酶 糖皮质激素 Tuberculosis pleurisy Veuous catheter Urokinase Glueocortieoids
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