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预注射右旋美托咪啶抑制芬太尼呛咳反应的临床观察 被引量:7

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摘要 目的:观察静脉预先注射右旋美托咪啶对全麻诱导期间芬太尼诱发呛咳反应的抑制作用。方法:选择100例ASAⅠ~Ⅱ级全麻择期手术患者,随机分为右旋美托咪啶组和对照组。所有患者麻醉诱导时经外周静脉给予芬太尼4μg/kg,右旋美托咪啶组在静脉给予芬太尼前静注右旋美托咪啶0.5μg/kg,而对照组则静注等量生理盐水。观察芬太尼呛咳的发生率和程度、诱导前后血流动力学的变化及相关并发症。结果:两组患者在性别、年龄和体重等各方面比较差异均无显著性(P>0.05)。右旋美托咪啶组有11例(22.0%)患者发生了呛咳反应,而对照组有29例(58.0%)患者出现了呛咳反应,两组比较差异有显著性(P<0.05)。结论:预先静脉注射0.5μg/kg右旋美托咪啶可有效降低麻醉诱导期间芬太尼呛咳反应的发生率。
出处 《实用医学杂志》 CAS 北大核心 2012年第21期3633-3634,共2页 The Journal of Practical Medicine
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参考文献12

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