摘要
为考察全氟化合物的土壤生态毒性,以赤子爱胜蚓为模式生物,通过人工土壤染毒方法研究全氟辛酸(PFOA)对蚯蚓急性毒性、回避行为和SOD、CAT等抗氧化酶活性的影响。结果表明,PFOA对蚯蚓的急性毒性作用与染毒时间和染毒浓度相关,实验求得PFOA对蚯蚓毒性作用7和14d的LC50值分别为816.58和792.50mg·kg-1;蚯蚓在160mg·kg-1PFOA暴露浓度下表现出明显的回避反应。在10～120mg·kg-1PFOA长时间暴露下,蚯蚓体内SOD出现"低促高抑"的变化趋势,而GSH-Px则总体上被PFOA所抑制。
To investigate the soil ecotoxicity ofperfluorinated compounds （PFCs）, artificial soil test was adopt- ed to study the effects of perfluorooctanoic acid （PFOA） on the acute lethality, avoidance behavior and the activities of antioxidant enzymes. The results showed that the acute toxicity of PFOA on earthworm was relat- ed to the exposure time and concentration of PFOA. The 7 d and 14 d of LC50of PFOA on earthworm were 816.58 and 792.50 mg· kg ^-1, respectively. At the maximum test concentration of 160 mg- kg 1, the earthworm showed significant avoidance behavior. After a long period of exposure to 10 - 120 mg .kg ^-1PFOA, the an- tioxidant enzymes in earthworms such as SOD exhibited ailelopathic inhibition under high concentration and aUelopathic stimulation under low concentrations. But the GSH-Px was inhibited by PFOA.
出处
《生态毒理学报》
CAS
CSCD
北大核心
2012年第5期532-536,共5页
Asian Journal of Ecotoxicology
基金
国家自然科学基金青年基金项目(20907046)
关键词
PFOA
蚯蚓
急性毒性
回避行为
抗氧化酶
PFOA
earthworm
acute toxicity
avoidance behavior
antioxidant enzymes
