摘要
目的探讨坦度螺酮联合西酞普兰治疗伴有焦虑症状的抑郁症疗效。方法将56例伴有焦虑症状的抑郁症患者随机分成两组,各28例。治疗组在用西酞普兰基础上联合使用坦度螺酮治疗,对照组仅用西酞普兰治疗,疗程6周。采用汉密尔顿抑郁量表(HAMD)、汉密尔顿焦虑量表(HAMA)评定疗效,采用药物不良反应量表(TESS)于治疗6周末评定不良反应。结果 6周末治疗组HAMD和HAMA评分低于对照组。两组不良反应无显著差异。结论坦度螺酮联合西酞普兰治疗伴有焦虑症状的抑郁症的疗效优于单用西酞普兰。
Objective To study the efficacy of tandospirone combined citalopram on depression with anxiety.Methods A total of 56 patients who met with the criteria of CCMD-3 for depression with anxiety were randomly divided into tandospirone combined citalopram group and citalopram group with the treatment of 6 weeks.The efficacy was evaluated with Hamilton Rating Scale for depression（HAMD） and Hamilton Rating Scale for anxiety（HAMA）.The side effects were evaluated with Treatment Emergent Symptoms Scale（TESS）.Results The reduce rate of mean score of HAMD and HAMA in intervention group was significantly higher than that of control group.Two groups of side effects was similar.Conclusion Tandospirone combined citalopram has better effect in treatment of depression with anxiety.
出处
《中国医药指南》
2012年第30期407-408,共2页
Guide of China Medicine
