摘要
目的观察奥扎格雷钠和丁苯酞联合治疗急性脑梗死的疗效。方法将本院近两年收治的诊断明确的急性脑梗死患者64例随机分为治疗组和对照组,每组32例。治疗组在常规治疗的基础上口服丁苯酞200mg,每日3次;奥扎格雷钠80mg,每12小时1次,静脉滴注。对照组在常规治疗基础上奥扎格雷钠80mg,每12小时1次,静脉滴注。均以14d为1个疗程,按临床神经功能缺损评分标准于治疗前后进行疗效评定。结果治疗组总有效率与对照组相比,差异有统计学意义(P<0.05);每组治疗前后神经功能缺损评分比较差异均有统计学意义(P<0.05);两组治疗后神经功能缺损评分比较差异有统计学意义(P<0.05);两组在治疗前后均未见明显不良反应。结论奥扎格雷钠联合丁苯酞治疗急性脑梗死疗效明显提高,且无明显不良反应,可以推广应用。
Objective To observe the curative effect on conjoint use of Sodium Ozagrel and butylphthalide in the treattment of acute cerebral infarction.Methods sixty-four patients who were diagnosed as acute cerebral infarction clearly in our hospital in nearly two years were randomly divided into two groups：treatment group（32 cases） and control group（27 cases）.Patients in treatment group were treated with Butylphthalide（Po 200 mg tid） orally and meanwhile with the injection of Sodium Ozagrel（ivgtt 80 mg bid,every 12 h） intravenously on the basis of conventional treatment.Patients in control group were only treated with Sodium Ozagrel（ivgtt 80 mg bid,every 12 h） intravenously;The periods of treatment are both 14 days.The efficacy was evaluated according to standard clinical neurological deficit score before and after treatment.Results The total effective rate in treatment group compared with control group,the difference was statistically significance（P 0.05）;the difference of neurological deficit score before and after treatment in each group were statistically sig nificant（P 0.05）;specifically,the neurological deficit scores in two groups after treatment had a significant difference（P 0.05）.Additionally,there was no untoward reaction after treatment in both groups.Conclusion The results prove an improvement in curative effect of acute cerebral infarction with the conjoint use of Sodium Ozagrel and Butylphthalide,and without any untoward reaction.This method can be promoted.
出处
《中国当代医药》
2012年第29期74-75,共2页
China Modern Medicine
关键词
奥扎格雷钠
丁苯酞
急性脑梗死
不良反应
Sodium Ozagrel
Butylphthalide
Acute cerebral infarction
Untoward reaction
