摘要
目的探讨〈50岁PSA4～10μg／L患者前列腺穿刺的临床病理特点。方法本组22例，年龄24～49岁，平均43岁。患者均无前列腺癌家族史。PSA值4．17—9．74μg／L，平均7．08μg／L。穿刺的原因为游离／总PSA≤0．16（20例）和（或）直肠指检阳性（4例）。本组游离／总PSA为0．03～0．53，平均0．11；前列腺体积13～74ml，平均39ml；PSA密度0．08—0．61，平均0．23。超声检查发现低回声改变或MRI检查发现低回声结节而可疑前列腺癌者13例。22例均行经直肠超声引导下经直肠前列腺穿刺活检术。结果22例中确诊为前列腺腺癌1例（4．5％），结核2例（9．1％），前列腺炎症9例（40．9％），未见异常10例（45．5％）。20例游离／总PSA≤0．16患者中，1例确诊为前列腺腺癌；4例直肠指检阳性患者中，2例诊断为结核，1例为炎症。结论〈50岁PSA4—10μg／L的年轻人中，前列腺穿刺主要的临床病理特点可能是前列腺增生以及前列腺组织内的炎症。
Objective To discuss the prostate biopsy results in young men with age less than 50 years and with PSA 4 - 10 μg/L. Methods From January 2006 to December 2011, 22 patients with PSA 4 -10 μg/L underwent prostate biopsy for free/total PSA ≤0.16 （20 cases） and/or positive digital rectal examination （DRE） （4 cases）. The mean age was 43 years （range, 24 -49 years） , the mean PSA level was 7.08 μg/L （range, 4. 17 - 9.74 μg/L） , the mean free/total PSA level was 0. 11 （range, 0.03 - 0.53）. Radiologic suspicious lesion was founded in 13 cases. Clinicopathological data from these patients were reviewed. Results The results of the biopsy were 1 （4.5%） case of prostate cancer, 2 cases （9.1%） with tuberculosis, 9 cases （40.9%） with inflammation, 10 cases （45.5%） with benign tissue. In 20 cases with free/total PSA≤0.16, only 1 case was diagnosed as prostate cancer. In 4 cases with posi- tive DRE, tuberculosis （2 cases） and inflammation （1 case） were diagnosed. Conclusions The prostate cancer detection was rare in young men less than 50 years of age with PSA 4 - 10 μg/L. The most common cause was prostate hyperplasia with inflammation.
出处
《中华泌尿外科杂志》
CAS
CSCD
北大核心
2012年第11期840-842,共3页
Chinese Journal of Urology
关键词
前列腺特异抗原
直肠指检
活组织检查
针吸
前列腺肿瘤
Prostate-specific antigen
Digital rectal examination
Biopsy, needle
Prostatic neoplasms
