摘要
目的探讨埃索美拉唑治疗反流性食管炎的临床疗效及优越性。方法将142例反流性食管炎患者随机分为观察组和对照组各71例,两组患者均给予健康指导及莫沙比利治疗,观察组给予埃索美拉唑40mg/次口服治疗,对照组给予奥美拉唑40mg/次口服治疗,观察两组患者治疗前后症状改善情况,并进行疗效评定。结果观察组治疗后症状积分明显低于对照组(P<0.05);观察组总有效率为97.18%,明显高于对照组的84.51%(P<0.05);两组不良反应发生率比较无显著差异(P>0.05)。结论埃索美拉唑反流性食管炎具有疗效好、症状改善明显、不良反应少等优点,是目前治疗RE的一种较佳PPI类药物。
Objective Discuss the clinical efficacy and advantages of esomeprazole on the treatment of RE. Methods Divide 142 RE patients into two groups of the observation group and the control group, each with 71 patients. Patients of both groups are given health guidance and the Mosapride treatment. The observation group is given the oral treatment of taking 40mg esomeprazole each time, while the control group the oral treatment of taking 40mg omeprazole each time. Results The total efficacy of the observation group is 97.18%, obviously higher than 84.51% of the control group （P 〈 0.05）. There is no obvious difference between the occurrence rate of the adverse reactions of both groups （P〉 0.05）. Conclusion On treatment of RE, esomeprazole has the qualities of good efficacy, obvious changes of symptoms and few adverse reaction, etc. It is one of the best PPI medicines against RE.
出处
《当代医学》
2012年第32期127-128,共2页
Contemporary Medicine
