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帕金森病中微小RNA的研究进展

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摘要 1研究简介 1．1帕金森病（PD）PD又名震颤麻痹，是一种常见的、缓慢发生的老年性进行性神经系统退行性疾病。其病理改变以选择性中脑黑质多巴胺能神经元丧失和纹状体多巴胺含量明显减少为主要特征，临床表现为静止性震颤、肌强直、动作减少及平衡障碍等一系列神经系统症状。Tretiakoff发现，PD患者的中脑黑质中含有色素的神经细胞有明显的特异性变性、脱落、消失。
作者 李晟 刘伟 肖建新
机构地区 解放军
出处 《中华老年心脑血管病杂志》 CAS 北大核心 2012年第11期1226-1228,共3页 Chinese Journal of Geriatric Heart,Brain and Vessel Diseases
关键词 帕金森病 微RNAS 多巴胺 多态性 单核苷酸 细胞周期
分类号 R742.5 [医药卫生—神经病学与精神病学]
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参考文献24

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二级参考文献30

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中华老年心脑血管病杂志
2012年 第11期

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