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心理干预对改良根治术后乳腺癌化疗患者免疫功能及不良情绪的影响 被引量:35

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摘要 目的:探讨心理干预对改良根治术后乳腺癌化疗患者免疫功能及不良情绪评分的影响。方法:70例行改良根治术后乳腺癌化疗患者,随机分为对照组和干预组,两组均接受常规治疗和护理,干预组进行心理干预。采用放免法测定心理干预对患者外周血中IL-2、IL-4及TNF-γ的变化情况。采用症状自评量表、Zung抑郁量表、Zung焦虑量表3种心理行为评定量表进行评定心理干预效果。结果:心理干预对改良根治术后乳腺癌化疗患者外周血中IL-2和IL-4有显著增强作用(P<0.05),干预组TNF-γ水平有所增高,但无统计学差异(P>0.05)。化疗后两组患者心理评分均明显降低(P<0.05),与对照组相比,干预组不良心理评分降低更为显著,差异有统计学意义(P<0.05)。结论:心理干预可提高改良根治术后乳腺癌化疗患者部分血清细胞因子的含量,可能与提高机体免疫力相关;可改善干预组患者的不良情绪,是这类患者的有效辅助治疗手段。
出处 《中国妇幼保健》 CAS 北大核心 2012年第31期4855-4857,共3页 Maternal and Child Health Care of China
基金 吉林省科技厅资助项目〔20090950〕
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参考文献9

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