摘要
目的应用速度向量成像(VVI)技术评价不同左心室构型高血压患者左心房心肌应变(S)、应变率(SR)的变化特点,探讨其评价高血压患者左心房功能的价值。方法高血压患者64例,根据左心室心肌质量指数分为左心室构型正常组(LVN组,n=37)和左心室肥厚组(LVH组,n=27);对照组为25名健康体检者。超声采集心尖四腔观及两腔观的二维动态图像,应用VVI技术获取左心房前壁、下壁、侧壁及间隔的基底段和中间段S、SR曲线,测量收缩期峰值应变(εsys)、应变率(SRs)及舒张早期、舒张晚期峰值应变率(SRe、SRa)。结果与对照组比较,LVH组SRe降低、SRa增高(P均<0.05),LVN组SRe、SRa、SRs、εsys的差异均无统计学意义(P均>0.05);与LVN组比较,LVH组SRe、SRa、SRs、εsys的差异均无统计学意义(P均>0.05)。结论 VVI技术所测左心房心肌S/SR参数可以反映左心室肥厚的高血压患者左心房管道功能降低、辅泵功能增强,但对左心室构型正常的高血压患者的左心房功能改变的敏感性不足。
Objective To evaluate left atrial strain （S） and strain rate （SR） changes in primary hypertensive patients by using velocity vector imaging （VVI）, in order to explore the value of VVT for assessing left atrial function in hypertensive patients. Methods Sixty-four patients with primary hypertension were divided into normal left ventricular geometry （LVN） group （n=37） and left ventricular hypertrophy （LVH） group （n=27）. Twenty-five healthy participants were in cluded as the control group. Apical four- and two-chamber echocardiographic views were obtained in two-dimensional modes, and S/SR curves of eight atrial segments （basal and middle segments from anterior, inferior, septal and lateral walls） were derived by VVI software. Peak systolic S （εsys）, systolic SR （SRs）, early and late diastolic SR （SRe, SRa） were calculated. Results Compared with the control group, SRe decreased and SRa increased significantly in LVH group （P〈0.05）, while no statistical difference of SRe, SRa, SRs or csys was found in LVN group （all P〉0.05）, nor of SRe, SRa, SRs or csys between LVH and LVN groups （all P〉0. 05）. Conclusion S/SR parameters derived from VVI can re fleet the decreased conduit function and increased booster pump function of the left atria in hypertensive patients with left ventricular hypertrophy, but it is not sensitive for primary hypertension with normal left ventricular geometry.
出处
《中国医学影像技术》
CSCD
北大核心
2012年第11期1999-2002,共4页
Chinese Journal of Medical Imaging Technology
基金
广东省科技计划社会发展项目(2012B031800049)
广东省心血管用药研究基金(2011X01)
