摘要
目的探讨前庭自旋转试验(Vestibular Autorotation Test,VAT)检出前庭源性眩晕疾病的敏感性以及区别中枢与外周性损害的临床价值。方法①对155例前庭源性眩晕患者组和30例正常人(对照组)进行VAT测试。②将前庭源性眩晕组根据临床诊断标准分为前庭中枢性疾病组和前庭外周性疾病组,比较两组间的VAT指标的特异性。结果①前庭源性眩晕组中VAT结果异常率约占95%,与正常对照组比较差异有显著性(P<0.01)。②73%前庭中枢性疾病组病人出现水平增益增高,明显高于前庭外周性疾病组,差异有显著性(P<0.01)。77%前庭外周性疾病组病人水平增益降低,明显高于前庭中枢性疾病组,两者差异有显著性(P<0.01)。结论①VAT可以作为前庭源性眩晕疾病的一种敏感的筛查方法;②VAT的水平增益是在前庭源性眩晕疾病中帮助区别中枢与外周性损害的一种客观而敏感的指标;③VAT为眩晕患者早诊断、早治疗提供了无创、简便、客观的检查方法。
Objective The purpose of this study was to test the sensitivity and significance of vestibular autorotation test （ VAT ） in detecting vestibular abnormality and differentiating peripheral fi＂om central origins. Methods （1）VAT was performed with 155 patients with vestibular disorders （patient group） and 30 normal subjects （control group）.（2）The patient group was determined by both clinical and laboratory test criteria, and fia-ther divided into the central lesion group and peripheral lesion group. （3）VAT parameters were compared between the two patient sub-groups. Results （1）VAT showed statistically significant abnormality in patient group （95%） compared with control group （7%） （P 〈 0.01）. Most of patients had more than one abnormal parameter. （2）Most the patients with central lesion origin （73%） had increased horizontal gains. O） Most of the patients with peripheral lesion origin （ 77% ） had decreased horizontal gains. The difference was statistically significant between the two patient groups （P〈0.01）. Conclusions（1）VAT is sensitive tool to detect vestibular origin disorders. （2）VAT is useful means to objectively reveal the central or peripheral nature of the vestibular disorders. （3） VAT could provide a non-invasive, simple and objective screening method to early diagnosis and early treatment of vertigo.
出处
《中国中西医结合耳鼻咽喉科杂志》
2012年第5期353-357,共5页
Chinese Journal of Otorhinolaryngology in Integrative Medicine
