摘要
目的:本研究旨在探讨18F-FDG PET-CT对转移瘤患者原发灶诊断中的价值。方法:回顾性分析164例经病理学检查证实为转移的不明原发灶肿瘤患者为寻找原发灶而行18F-FDG PET-CT检查,待最终随访结束后对所有数据、资料进行统计处理分析。结果:18F-FDG PET-CT对肿瘤原发灶总检出率为51.2%(84/164),特异性97.3%(71/73),敏感性92.3%(84/91),准确度94.5%(155/164),阴性预测值91.0%(71/78),阳性预测值97.7%(84/86)。PET-CT对转移性腺癌、转移性鳞癌、转移性未分化癌3组常见病理类型转移瘤的原发灶检出率分别为54.0%(47/87)、56.8%(21/37)、40.0%(12/30)。经统计分析,3组转移瘤原发灶检出率之间无统计学差异。结论:18F-FDG PET-CT在寻找不明原发灶肿瘤原发灶中具有重要价值。
Objective： To evaluate the ISF-FDG PET-CT in detecting primary foci in cases of suspected metastatic tumor. Methods： One hundred and sixty-four patients with pathologically proved metastasis of unknown primary tumor underwent ^18F- FDG PET-CT scan. Statistical analysis was performed after the final follow up. Result： The total positive rate, specificity, sen- sitivity, accuracy, negative predictive value and positive predictive value were 51.2%（84/164）, 97.3%（71/73）, 92.3%（84/91）, 94.5%（155/164）, 91.0%（71/78）, 97.7%（84/86） respectively. The positive rate of the primary loci for metastatic adenoeareinoma, metastatic squamous carcinoma and metastatic undifferentiated carcinoma were 54.0%（47/87）, 56.8%（21/37） and 40.0%（12/30） respectively. According to the statistical analysis, there was no statistical difference among the positive rate of the three groups. Conclusion： ^18F-FDG PET-CT might be of importance in ＇the detection of primary site in unknown primary tumors
出处
《中国临床医学影像杂志》
CAS
2012年第10期722-726,共5页
Journal of China Clinic Medical Imaging
