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西布曲明的合成改进 被引量:5

An Improvement on Synthesis of Sibutramine
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摘要 报道 5-羟色胺和去甲肾上腺素再摄取抑制剂西布曲明 (sibutramine) The 5 hydroxytryptamine and noradrenaline reuptake inhibitor—sibutramine was synthesized by an improved route.This route optimized the synthetic process,the total yield was 48%.
出处 《中国药物化学杂志》 CAS CSCD 2000年第2期129-130,共2页 Chinese Journal of Medicinal Chemistry
关键词 肥胖证 西布曲明 合成改进 制备 obesity sibutramine improvement on synthesis
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参考文献1

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同被引文献33

  • 1梁小蕊,方啸天,牛妍懿.大黄素红外光谱的理论研究[J].当代化工,2020(6):1131-1134. 被引量:2
  • 2吴继禹,张春红,刘建飞.催化剂KF/Al_2O_3在西布曲明合成中的应用[J].安徽医药,2005,9(8):637-637. 被引量:1
  • 3吕秀娟,梅璐璐,施小新.手性拆分剂L-二苯甲酰酒石酸和L-二乙酰酒石酸的合成工艺研究[J].精细化工中间体,2005,35(4):12-14. 被引量:10
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