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前列地尔对失代偿期肝硬化合并腹水的疗效观察 被引量:2

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摘要 目的:观察前列地尔辅助治疗失代偿期肝硬化合并腹水的疗效。方法:选择89例失代偿期肝硬化合并大量腹水患者,随机分成2组,对照组予基础综合治疗,治疗组在综合治疗的基础上加用前列地尔。观察平均尿量、腹水消退时间以及治疗2周时肝功恢复情况。结果:治疗组与对照组相比,治疗期间平均24h尿量分别为(2680±236)ml和(1939±310)ml,平均腹水消退时间分别为(4.23±1.15)天和(6.89±3.48)天,治疗2周检查TBIL分别为(26.9±12.4)和(42.6±23.1)μmol/L;ALT分别为(38.3±11.5)和(47.1±19.3)U/L;ALB分别为(32.1±5.4)和(32.6±4.8);PTa分别为(62.1±16.2)%和(53.3±12.8)%。治疗组在24小时尿量、腹水消退时间以及肝功能改善方面均较对照组有显著性差异(P<0.05)。结论:前列地尔作为辅助用药可缩短失代偿期肝硬化合并腹水患者的尿量,缩短住院时间,并使肝功能改善更显著。
出处 《中国美容医学》 CAS 2012年第07X期233-234,共2页 Chinese Journal of Aesthetic Medicine
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  • 1杨丽华 曹霆华.重症肝炎新论[M].北京:人民卫生出版社,1997.275.
  • 2Baek Y,Nakano H,Kumada K,et al.Administration of prostaglandin E1 reduces post-operative hepatocellular damage and restores hepatic integrity in patients undergoing hepatectomy [J].Hepatogastroenterology,1999,46(27):1836-1841.
  • 3Iribe G,Ohnishi Y,Hayashi Y,et al.Effect of prostaglandin E1 and nitroglycerin on portal venous flow during hypothermic extracorporeal circulation:assessment by transesophageal echography [ J ].Acta Anaesthesiol Scand,1999,43(5):520-525.
  • 4Nakagohri T,Asano T,Uematsu T,et al.The effects of prostaglandin E1 and tyrosine kinase inhibitors on energy status and protein synthetic ability in hepatic ischemia-reperfusion injury [J].Surg Today,1998,28(5):517-521.
  • 5Buko VU,Sadovnichy VV.Cytochrome P-450 and free radical generation in rat liver microsomes under the influence of prostaglandin E1 [J].Biochem Mol Biol Int,1996,39(6):1177-1184.
  • 6Muntane J,Montero JL,Marchal T.Effect of PGE1 on TNF-alpha status and hepatic D-galactosamine-induced apoptosis in rats[ J ].J Gastroenterol Hepatol,1998,13(2):197-207.
  • 7Iwata K,Shimasu M,Wakabayashi G,et al.Intraportal perfusion of prostaglandin E1 attenuates hepatic postischaemic microcirculatory impairments in rats [ J ].J Gastroenterol Hepatol,1999,14(7):634-641.
  • 8Natori S,Fujii Y,Kurosawa H,et al.Prostaglandin E1 protects against ischemia-reperfusion injury of the liver by inhibition of neutrophil adherence to endothelial cells [ J ].Transplantation,1997,15(11):1514-1520.
  • 9Lou J,Buhler L,Deng S,et al.Inhibition of leukocyte adherence and transendothelial migration in cultured human liver vascular endothelial cells by prostaglandin El [ J ].Hepatology,1998,27(3):822-828.
  • 10Kishimoto S,Sakon M,Umeshita K,et al.The inhibitory effect of prostaglandin El on oxidative stress-induced hepatocyte injury evaluated by calpain-mu activation [ J ].Transplantation,2000,15(11):2314-2319.

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