摘要
目的分析评价门诊抗菌药物应用及不合理用药状况。方法从西南大学医院2010年1-6月药库计算机管理软件中查询门诊药房抗菌药物各品种的总量及金额,对金额及用药频度(DDDs)进行分析排序。每月随机抽取处方1 000张,共6 000张处方,对处方用药进行统计分析。结果抗菌药头孢菌素类用药金额比例最高,达45.45%。门诊抗菌药物的DDDs前10位的药物中头孢菌素类占3种。DDDs排序前4位为阿莫西林、左氧氟沙星、头孢呋辛和阿奇霉素。抗菌药使用中不合理处方占35.64%,存在用法用量、联合用药不合理、无指征用药、用药与诊断不符等问题。结论我院门诊抗菌药物使用比例较高,以头孢菌素类抗菌素应用最多,存在不合理用药的问题,医院需加强对抗菌药物合理使用的监控与管理。
Objective To evaluate the outpatient antibiotics application and irrational drug use.Method Various kinds of outpatient antibiotics and their amount were searched in the drug storehouse computer management software of the hospital of southwest university from January to June in the year 2010,and the amount and DDDs were analyzed and ranked.1 000 prescriptions were chosen at random each month and prescription drugs were statistically analyzed with a total amount of 6 000 prescriptions.Results The drug-used amount of antibiotic cephalosporins was the highest with a percentage of 45.45%;in the outpatient antibiotics with their DDDs ranking top ten,there were 3 kinds of cephalosporins;drugs with their DDDs ranking top four were amoxicillin,levofloxacin,cefuroxime and azithromycin respectively;35.64% of prescriptions concerning use of antibiotics were irrational prescriptions,and there existed problems such as irrational dosage and improper drug combination,drugs' being used without medical indication and not in compliance with diagnosis and the like.Conclusion The utilization rate of outpatient antibiotics in our hospital is relatively high and the cephalosporins antibiotics is the most commonly used drug;there is irrational use of drug and the hospital should strengthen its monitor and management on rational use of antibiotics.
出处
《保健医学研究与实践》
2012年第1期43-46,共4页
Health Medicine Research and Practice