摘要
目的探讨冠状动脉病变积分(CAS)与血压变异性及颈动脉硬化的关系。方法 820例行冠状动脉造影者,其中男性518例,女性302例,年龄30～84岁,平均年龄57.28±9.44岁。以标准Judkins法行冠状动脉造影术,计算机定量分析系统(QCA)分析冠状动脉狭窄程度并计算冠状动脉病变积分(CAS)。所有患者行动态血压监测,颈动脉超声检查,并进行颈动脉硬化分型及等级积分。结果年龄、性别、体重指数、24小时收缩压标准差(24hSTDs)、24小时最大平均动脉压、高血压病史、2型糖尿病病史、高密度脂蛋白胆固醇、颈动脉硬化积分均与CAS有显著相关关系,经多因素logstic回归分析显示,24hSTDs和颈动脉粥样硬化积分与CAS呈显著正相关。结论 24hSTDs、颈动脉粥样硬与CAS密切相关,是冠心病发生发展的良好的预测指标。
Objective To investigate the relationship between coronary artery disease and blood pressure variability（BPV）,carotid arterial atherosclerosis.Methods Coronary angiography（standard Judkins approach）was performed on 820 patients（518 males and 302 females）between the age of 30 and 84（mean 57.28±9.44）years old.The severity of coronary artery lesions was analyzed by quantitative computer analysis system（QCA）and CAS was calculated.Ambulatory blood pressure measurement（ABPM）,carotid artery ultrasonography were recorded,and then carotid artery scores and the type of carotid artery atherosclerosis were involved.Results age,sex,BMI,24hSTDs,24 h MAPmax,hypertension,T2DM,HDL-C,carotid artery scores were significantly associated with coronary artery disease.Multivariate regression analysis showed that 24hSTDs and carotid artery scores were significantly related to coronary artery disease.Conclusion 24hSTDs and carotid artery scores were significantly related to coronary artery disease,and that could be used to predict to the development of coronary artery disease.
出处
《中国老年保健医学》
2012年第5期5-8,共4页
Chinese Journal of Geriatric Care
关键词
冠状动脉疾病
冠状动脉造影
血压变异性
颈动脉粥样硬化
coronary artery disease Coronary angiography blood pressure variability（BPV）carotid arterial atherosclerosis
