摘要
目的探讨纳洛酮联合氨茶碱治疗早产儿原发性呼吸暂停的效果和安全性,为以后出现原发性呼吸暂停早产儿的治疗和用药提供参考。方法将我院收治的112例出现原发性呼吸暂停的早产儿随机分为对照组56例和治疗组56例,其中对照组单独采用氨茶碱进行治疗,治疗组在对照组的基础上加静脉注射纳洛酮,比较两组的治疗效果。结果从临床症状消退情况来看,治疗组比对照组的治疗效果更好,治疗组治愈率显著高于对照组,两者差异有统计学意义(P<0.05);且治疗组早产儿无明显不良反应发生。结论纳洛酮联合氨茶碱治疗早产儿原发性呼吸暂停疗效显著,且未见明显不良反应,值得在临床上推广。
Objective To observe and analyze the effect of~ naloxone combined with aminophyUine in treatment of primary apnea of premature infants and the clinical safety, providing reference for the treatment and pharmacy of primary apnea of premature infants. Methods A total of 112 premature infants who suffering primary apnea were divided into two groups, each 56 cases. Treated premature infants in the control group with aminophylline only, and in the treatment group added naloxone treatment on the basis of aminophylline, compared the effect of two groups. Results Evaluate from clinical symp- toms subsided situation, the effect of the treatment group was better than the control group, besides, the effective rate of the treatment group was much higher than the control group. The two groups showed significant difference by statistical pro- cessing （P 〈 0.05 ）. And there were no untoward effects happened on the premature infants treated with naloxone. Conclu- sion Naloxone combined with aminophylline in treatment of primary apnea of premature infants showed significant effect, and didn＇t cause untoward effects, worthy of being applied in clinic.
出处
《中国现代医生》
2012年第29期70-71,共2页
China Modern Doctor
