摘要
目的探讨两种子宫动脉栓塞方案治疗子宫肌瘤的临床效果和不良反应。方法将已确诊的子宫肌瘤患者78例,随机分为A组和B组,每组各39例。A组以聚乙烯醇颗粒作为栓塞剂,B组以平阳霉素乳剂+明胶海绵作为栓塞剂,两组患者均接受超选择性子宫动脉栓塞术治疗,观察并比较两组患者术前和术后3、6和12个月的临床症状、瘤体改变程度以及月经情况。结果两组患者在手术时间、疼痛时间、住院时间等方面无统计学意义,患者术后平均随访时间(13.8±2.1)个月,两组患者在3、6和12个月瘤体缩小率方面无统计学意义(P>0.05),且术后6个月两组患者月经改善情况差异不显著(P>0.05),均无明显不良反应。结论平阳霉素乳剂+明胶海绵与聚乙烯醇颗粒用作栓塞剂治疗子宫肌瘤具有相同的临床效果和安全性,且价格较为低廉,值得临床推广。
Objective To investigate the clinical effect and bad reaction of two different uterine artery embolization meth- ods in treating patients with uterine fibroids. Methods All 78 patients with uterine fibroids were divided into two groups for each 39. Patients in group A were given polyvinyl alcohol as embolic agent,others in group B were given pinyangmycin emulsion＋ gelatin sponge as embolic agent, all the patients were given super-selective uterine artery embolization,the clin- ical symptoms, change of tumor and menstrual status were compared before and after 3,6 and 12 month of treatment. Results There was no difference between two groups in the time of surgery, pain, hospitalization and the rate of tumor re- gression in 3,6 and 12 month after treatment（P 〉 0.05）. Conclusion Pinyangmycin emulsion＋gelatin sponge as embolic a- gent has the same effect as polyvinyl alcohol, and has a virtue of cheap and safe, deserve to clinical.
出处
《中国现代医生》
2012年第26期33-34,共2页
China Modern Doctor
关键词
子宫肌瘤
子宫动脉栓塞
聚乙烯醇
平阳霉素
明胶海绵
Uterine fibroids, Uterine artery embolization
Polyvinyl alcohol
Pinyangmycin emulsion
Polyvinyl alcohol
