摘要
目的评价脑心通治疗脑梗死的疗效和安全性。方法选用中国生物医学文献数据库(CBM)、中国期刊全文数据库(CNKI)、中文科技期刊数据库(VIP)、万方数据资源系统数据库(W.F)、美国国立医学图书馆(PubMed)、Cochrane图书馆(后文以"C.L"简称)中相关内容等作为资料源,对其1995年1月—2011年4月正式刊载的符合纳入标准的58篇有关脑梗塞的脑心通治疗的随机对照试验(RCT)文献进行Meta分析。结果脑心通胶囊组临床疗效有效率比对照组高22%;治疗后神经功能缺损评分明显低于对照组;血液流变学指标明显低于对照组。脑心通胶囊组与对照组比较,治疗后三酰甘油、红细胞比容差异无统计学意义。结论脑心通治疗脑梗塞的疗效确切,与其他药物相比较,具有很好的应用前景。
Objective To evaluate the efficacy and safety of Naoxintong capsule（NXTC） for treatment of cerebral infarction.Methods Controlled randomized clinical trials from 1995 through 2011 were retrieved in Chinese Biomedical Literature Database（CBM）,the Chinese Journal Full-Text Database（CNKI）,Weipu Journal Database（VIP）,Wanfang Database,PubMed,Cochrane.Rev Man 4.3 software was provided by Cochrane Collaboration.Meta-analysis was conducted including 58 articles meeting the inclusion criteria.Results The clinical curative effect was 22% in NXTC group,and it was higher than that in control group.The scores neural function defect scale in NXTC group was significantly lower than that in control group.The hemorrheologic indices were significantly lower than that in control group after treatment.There was no significant difference of triglyceride and the red blood cells hematocrit after the treatment.Conclusion NXTC was efficacy and safety for treatment of cerebral infarction.
出处
《中西医结合心脑血管病杂志》
2012年第10期1182-1186,共5页
Chinese Journal of Integrative Medicine on Cardio-Cerebrovascular Disease
关键词
脑心通
脑梗死
META分析
Naoxintong capsule
cerebral infarction
metda-analysis
