摘要
目的探讨盐酸纳美芬在急性乙醇中毒中的应用。方法将89例重度乙醇中毒患者随机分为治疗组49例和对照组40例。对照组给予常规治疗,治疗组在此基础上加用盐酸纳美芬,观察并比较两组患者清醒时间。结果治疗组用药30 min病情明显好转,病情稳定。与对照组相比,治疗组的症状缓解时间及后遗效应消失时间明显优于对照组(P<0.05)。结论在常规治疗的基础上联合应用盐酸纳美芬抢救早期急性乙醇中毒疗效肯定。
Objective To investigate the effect of nalmefene hydrochloride in treating acute alcoholism. Methods Eighty-nine cases of mild and severe alcoholism were randomly divided into the treatment group（49 cases） and the control group（40 cases）. The conventional treatment was performed in the control group. On this base, the treatment group was added with nalmefene hydrochloride. The awakening time was observed and compared between the two groups. Results The disease condition in the treatment group was obviously improved with stability in 30 min. The symptoms relief time and the disappearing time of residual effects in treatment group were significantly superior to the control group. Conclusion On the basis of the conventional treatment, combination use of nalmefene hydrochloride has definite effect in rescuing early alcoholism.
出处
《中国药业》
CAS
2012年第21期52-52,共1页
China Pharmaceuticals
关键词
纳美芬
乙醇
中毒
nalmefene
alcohol
poisoning
