摘要
目的观察立普妥(阿托法他汀)治疗冠心病患者高敏C反应蛋白(hsCRP)及总胆固醇(CHDL),甘油三酯(TG),低密度脂蛋白(LDL-C)的变化。方法 170例冠心病患者随机分对照组(未服任何调脂药,82例),治疗组(服立普妥20mg/d,88例),测定治疗后hs-CRP和血脂数值,观察治疗后hsCRP CHDL、TG)及LDL-C的变化。结果治疗组治疗前后hsCRP、CHDL、TG及LDL-C的变化差异有统计学意义。结论立普妥在治疗冠心病中,不但可以使血脂水平明显降低,还能使hsCRP水平明显降低,从而有利于缓解动脉硬化的过程。
Objective To investigate the effect of Lipitor （atorvastain） on patients with coronary heart disease, high sensitivity （hsCRP） and the changes of total cholesterol （CHDL））, triglyceride （TG）, low density lipoprotein （LDL--C）. Methods 170 CHD patients were randomly divided into con- ventional treatment group （not taking any cholesterol lowering agents, 82 cases）, the treatment group （taking Lipitor 20rag / d, 88 cases）. Measured hs--CRP and lipids and observed the data changes of hsCRP, CHDL, TG and LDL--C after treatment in two groups. Results In Lipitor treatment group, the data changed and differentces of hs--CRP, CHDL, TG and LDL--C after treatment were statistical- ly significant. Conclusions In treating CHD, Lipitor is highly effective in lowering blood fat level,and hs--CRP level as well,thus it helps to ease the process of atherosclerosis.
出处
《齐齐哈尔医学院学报》
2012年第20期2769-2770,共2页
Journal of Qiqihar Medical University
