摘要
肝素诱导的血小板减少症患者预后差,病死率高,大大增加了体外循环手术的风险。对其早期诊断和选择一种安全有效的药物替代肝素抗凝是这类患者接受体外循环手术的关键。我们对肝素诱导的血小板减少症发病机制、实验室检查、诊断以及体外循环抗凝管理进行综述。
Patients with heparin-induced thrombocytopenia have a poor prognosis and high mortality,thus surgical risk under extracorporeal circulation increased.Early diagnosis,safe and effective alternative anticoagulation strategy are crucial for these patients to receive extracorporeal circulation surgery.This review focuses on the pathophysiology,laboratory examination,diagnosis and alternative anticoagulation strategy of extracorporeal circulation for patients with heparin-induced thrombocytopenia.
出处
《中国胸心血管外科临床杂志》
CAS
2012年第5期559-562,共4页
Chinese Journal of Clinical Thoracic and Cardiovascular Surgery
关键词
肝素诱导的血小板减少症
体外循环
抗凝
Heparin-induced thrombocytopenia
Extracorporeal circulation
Anticoagulation
