摘要
目的:探讨影响消化性溃疡并大出血预后的相关因素。方法:回顾性分析2006-2011年在我院住院治疗的326例消化性溃疡并大出血患者的临床资料,设患者年龄、性别、吸烟、饮酒、既往消化性溃疡病史、NSAID服药史、出血方式、血红蛋白含量、休克、输血、溃疡部位、溃疡大小、内镜表现、HP感染、乙肝病毒感染、伴发疾病、伴发疾病累及器官数这17个因素为可能影响预后的因素,应用Logistic逐步回归分析方法分析其与消化性溃疡并大出血预后的关系。结果:Logistic逐步回归结果提示年龄、休克和伴发疾病为患者死亡的主要影响因素;年龄、血红蛋白含量、休克、溃疡大小和内镜Forrest分级为患者发生再出血的主要影响因素。结论:消化性溃疡并大出血治疗预后受多种因素共同影响,临床上应加以重视,以便指导和选择个体化治疗方案,改善患者预后。
Objective：To explore the influencing factors of prognosis in massive hemorrhage complicated with peptic ulcer.Methods：Retrospective analysis 326 patients with massive hemorrhage complicated with peptic ulcer hospitalized in our hospital from 2006 to 2011.To suppose 17 factors as possible prognostic factors,including age,sex,smoking,drinking,peptic ulcer history,history of using of NSAID,kind of bleeding,hemoglobin value,shock,transfusion,location of ulcer,size of ulcer,expression under endoscopy,helicobacter pylori infection,hepatitis B virus infection,concomitant diseases and the number of organs associated with concomitant diseases.Logistic stepwise regression was used to analysis the relationship of these factors and the prognosis of massive hemorrhage complicated with peptic ulcer.Results：Logistic stepwise regression results indicated that age,shock and concomitant diseases are the influencing factors of death.Age,hemoglobin value,shock,size of ulcer and forrest classification are the influencing factors of recurrent bleeding.Conclusion：The prognosis of massive hemorrhage complicated with peptic ulcer depends upon many factors.More attention should be paid in clinical practice to guide and select the individualized treatment plan and improved the prognosis of the patients.
出处
《医学理论与实践》
2012年第20期2472-2474,共3页
The Journal of Medical Theory and Practice
