摘要
儿童散发性伯基特淋巴瘤(BL)属于高度侵袭性淋巴瘤,在形态学、免疫表型和分子遗传学等方面与弥漫性大B细胞淋巴瘤(DLBCL)及介于DLBCL和BL之间的未分类B细胞淋巴瘤(DLBCL/BL)有部分重叠,但亦有其独特的表征。通过对BL病理、发病机制及预后的了解,增强对该病的认识,并在诊断时与DLBCL、DLBCL/BL进行鉴别,有利于临床正确的治疗及预后判断。
Children with sporadic Burkitt' s lymphoma (BL) is a highly aggressive lymphoma. It partly overlaps with diffuse large B cell lymphoma (DLBCL) and unclassified B cell lymphoma (DLBCL/BL) which 'is between DLBCL and BL in the morphological, immunophenotypic and molecular genetic aspects, but it has its unique characterization. Enhancing awareness of the disease based on the BL pathology, pathogenesis and prognosis of understanding, at the time of diagnosis and identificate with DLBCL and DLBCL/BL at the tine of diagnosis will be beneficial to clinical correct treatment and prognosis.
出处
《白血病.淋巴瘤》
CAS
2012年第10期629-631,共3页
Journal of Leukemia & Lymphoma
关键词
淋巴瘤
病理诊断
免疫表型
分子遗传学
Lymphoma
Pathological diagnosis
Immunophenotype
Molecular genetics