摘要
目的:通过对小鼠的生理生化指标的检测分析,探讨生半夏和竹沥半夏的寒热药性。方法:采用灌胃分别给予小鼠生半夏、竹沥半夏的水煎液11d,测量并记录小鼠的体重、饮水量、进食量、体温、耗氧量、肝组织总蛋白含量、NaK-ATPase活性、肝脏系数的变化,来研究其寒热之药性。结果:与对照组比较,生半夏组、竹沥半夏组对小鼠的体重、进食量、肝脏系数的变化均无明显区别;生半夏组可使小鼠的饮水量、体温、耗氧量、NaK-ATPase活力、肝脏组织总蛋白含量增加;竹沥半夏组可使小鼠的饮水量、体温、耗氧量、NaK-ATPase活力、肝脏组织的蛋白含量降低。结论:生半夏和竹沥半夏药性的差异可通过饮水量、体温、耗氧量、NaK-ATPase活力、肝脏组织总蛋白含量等生理生化指标得以反映,该结果与传统的"竹沥能转半夏之温热之性而为寒凉"的理论相一致。
Objective： Testing the physiological and biochemical parameters in mice, to evaluate the na- ture of unprocessed Rhizoma Pinelliae （RP） and Rhizoma Pinelliae With Bamboo Vinegar Processed （RP- BVP）. Methods： Measured weight, water intake, food intake, body temperature, oxygen consumption, total pro- tein content of liver tissue, Na - K - ATPase activity, liver coefficient of mice after giving the water decocted solu- tion of RP and RP - BVP intragestrically 11 days. Results ： Compared with control group, weight, food intake, liv- er coefficient had no significant difference in RP and RP - BVP group ; Compared with control group, water intake, body temperature, oxygen consumption, Na - K - ATPase activity, total protein content of liver tissue increased in RP group; oxygen consumption, the liver tissue total protein content, Na - K - ATPase activity reduced in RP - BVP group. Conclusion ： water intake, body temperature, oxygen consumption, Na - K - ATPase activity, total protein content of liver tissue can be used to evaluate the cold and heat nature of RP and RP - BVP.
出处
《云南中医学院学报》
2012年第5期11-14,29,共5页
Journal of Yunnan University of Traditional Chinese Medicine
基金
陕西省中医药管理局项目(NO:200713)
关键词
生半夏
竹沥半夏
寒热药性
生理生化指标
RP
RP - BVP
cold or heat nature
physiological and biochemical parameters
